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Details on Person DT:HBEGF:CD9 [plasma membrane]

Class:Id	Complex:5334772
_displayName	DT:HBEGF:CD9 [plasma membrane]
_timestamp	2022-02-07 18:37:41
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5334781] D'Eustachio, Peter, 2014-02-26
disease	[Disease:5334089] diphtheria
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasComponent	[EntityWithAccessionedSequence:51717] CD9 [plasma membrane] [Homo sapiens] [Complex:5334768] DT A:B [plasma membrane] [Corynephage beta] [EntityWithAccessionedSequence:5334088] DT(226-567) disulfide bonded [plasma membrane] [Corynephage beta] [EntityWithAccessionedSequence:5334090] DT(33-225) disulfide bonded [plasma membrane] [Corynephage beta] [EntityWithAccessionedSequence:2179406] HBEGF(20-208) [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5334775] Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen [LiteratureReference:5334777] Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity
modified	[InstanceEdit:5643874] D'Eustachio, Peter, 2014-11-18 [InstanceEdit:8959586] Weiser, JD [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9763875] D'Eustachio, Peter, 2022-02-07 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name	DT:HBEGF:CD9
relatedSpecies	[Species:5333948] Corynephage beta
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5648762] R-HSA-5334772.20
(input)	[BlackBoxEvent:5336422] Clathrin-mediated endocytosis of DT:HBEGF:CD9 [Homo sapiens]
(output)	[Reaction:5336417] DT A:B binds HBEGF and CD9 on the target cell surface [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9896793] Update Tracker - [Complex:5334772] DT:HBEGF:CD9 [plasma membrane] - v60:[removeSpecies] [_UpdateTracker:9904056] Update Tracker - [Complex:5334772] DT:HBEGF:CD9 [plasma membrane] - v80:[add_removeHasComponent]
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No pathways have been reviewed or authored by DT:HBEGF:CD9 [plasma membrane] (5334772)