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Details on Person HPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP

Class:IdReaction:5334740
_displayNameHPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP
_doReleaseFALSE
_timestamp2016-07-15 23:49:49
authored[InstanceEdit:140952] Gillespie, ME, 2004-08-24 21:33:15
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:5334743] Gillespie, Marc E, 2014-02-26
disease[Disease:5334690] papillomavirus infectious disease
edited[InstanceEdit:3371404] Shamovsky, V, 2013-05-13
input[EntityWithAccessionedSequence:66376] TRADD [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:168651] RIPK1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:66370] TRAF2 [cytosol] [Homo sapiens]
[DefinedSet:3371401] TNF-α trimer:TNFR1 trimer [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:66376] TRADD [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:66376] TRADD [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:66370] TRAF2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:66370] TRAF2 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:2672210] The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis
modified[InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00
[InstanceEdit:109912] Joshi-Tope, G, 2004-01-21 22:18:55
[InstanceEdit:110070] Joshi-Tope, G, 2004-01-28 14:40:07
[InstanceEdit:140952] Gillespie, ME, 2004-08-24 21:33:15
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:386963] Williams, MG, 2008-11-27 15:33:38
[InstanceEdit:2648974] D'Eustachio, P, 2012-11-21
[InstanceEdit:3006723] Jassal, B, 2013-02-01
[InstanceEdit:3371406] Shamovsky, V, 2013-05-13
[InstanceEdit:3465520] Shamovsky, V, 2013-05-17
[InstanceEdit:3597633] Shamovsky, V, 2013-05-22
[InstanceEdit:3632866] Shamovsky, V, 2013-05-28
[InstanceEdit:5334691] Gillespie, Marc E, 2014-02-24
[InstanceEdit:5338607] Gillespie, Marc E, 2014-03-03
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
nameHPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP
normalReaction
output[Complex:140946] TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[NegativeRegulation:2672216] Negative regulation by 'viral E6 [cytosol]'
regulationReference[RegulationReference:9641532] Negative regulation by 'viral E6 [cytosol]' The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis
reviewed[InstanceEdit:386956] Silverman, N, Lemaitre, B, 2008-06-20 10:21:55
[InstanceEdit:3597630] Pop, Cristina, Salvesen, Guy S., 2013-05-22
revised[InstanceEdit:3465563] Shamovsky, V, 2013-05-17
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8904567] R-HSA-5334740.1
summation[Summation:74302] Once the TNF-α:TNFR1:TRADD:RIPK1 complex has been formed the...
(hasEvent)[Pathway:5334688] Papillomavirus Host Interactions [Homo sapiens]
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No pathways have been reviewed or authored by HPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP (5334740)