Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person HPV 16 codes for two oncogenes, E6 and E7. E7 is best known ...

Class:IdSummation:5334737
_displayNameHPV 16 codes for two oncogenes, E6 and E7. E7 is best known ...
_timestamp2014-03-03 18:32:37
created[InstanceEdit:5334743] Gillespie, Marc E, 2014-02-26
modified[InstanceEdit:5338611] Gillespie, Marc E, 2014-03-03
textHPV 16 codes for two oncogenes, E6 and E7. E7 is best known for its ability to bind to and inactivate the retinoblastoma protein. The E6 protein of HPV 16 mediates the rapid degradation of the tumor suppressor p53, although this is not the only function of E6 and cannot completely explain its transforming potential. E6 has additional biological and transforming activities that appear to be independent of p53. Mechanistically, these activities are a consequence of the interactions of E6 with cellular proteins.
(summation)[Pathway:5334688] Papillomavirus Host Interactions [Homo sapiens]
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No pathways have been reviewed or authored by HPV 16 codes for two oncogenes, E6 and E7. E7 is best known ... (5334737)