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Details on Person 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC

Class:Id	Reaction:5333615
_displayName	80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC
_doRelease	TRUE
_timestamp	2015-11-20 15:08:04
authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359049] GTPase activity of 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5333616] Williams, MG, 2014-02-19
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
inferredFrom	[Reaction:5333610] Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec [Rattus norvegicus]
input	[Complex:5359044] 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] [Homo sapiens] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5359334] Ribosomal protein L30 is a component of the UGA-selenocysteine recoding machinery in eukaryotes
modified	[InstanceEdit:5333618] Williams, MG, 2014-02-19 [InstanceEdit:5357739] Williams, MG, 2014-03-26 [InstanceEdit:5359121] Williams, MG, 2014-04-08 [InstanceEdit:5359394] Williams, MG, 2014-04-09 [InstanceEdit:5422928] Williams, MG, 2014-05-06 [InstanceEdit:5422935] Williams, MG, 2014-05-06 [InstanceEdit:6793107] D'Eustachio, Peter, 2015-08-30 [InstanceEdit:6793354] D'Eustachio, Peter, 2015-09-01 [InstanceEdit:6804161] D'Eustachio, Peter, 2015-10-08 [InstanceEdit:6804183] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC
output	[Complex:5359053] 80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] [Homo sapiens] [Complex:5359051] EEFSEC:GDP [cytosol] [Homo sapiens] [GenomeEncodedEntity:5357732] tRNA(Sec) [cytosol] [Homo sapiens] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:2408529] Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome [Homo sapiens] [Reaction:2408509] Sec-tRNA(Sec) binds to EEFSEC:GTP [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812350] R-HSA-5333615.2
summation	[Summation:5359355] The complex consisting of selenocysteinyl (Sec) transfer RNA...
(hasEvent)	[Pathway:2408557] Selenocysteine synthesis [Homo sapiens]
(precedingEvent)	[Reaction:2408526] tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer [Homo sapiens]
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No pathways have been reviewed or authored by 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC (5333615)