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Details on Person Removal of the second glucose by glucosidase II

Class:Id	Reaction:532667
_displayName	Removal of the second glucose by glucosidase II
_doRelease	TRUE
_timestamp	2010-12-02 14:39:11
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:532675] glucan 1,3-alpha-glucosidase activity of glucosidase II [endoplasmic reticulum lumen]
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:532665] Jassal, B, 2010-03-02
edited	[InstanceEdit:532665] Jassal, B, 2010-03-02
input	[Complex:901051] unfolded protein:(Glc)2 (GlcNAc)2 (Man)9 (Asn)1:malectin [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:532700] The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo
modified	[InstanceEdit:532702] Jassal, B, 2010-03-02 [InstanceEdit:749517] Jassal, B, 2010-05-19 [InstanceEdit:901079] Jassal, B, 2010-07-02 [InstanceEdit:933772] Jassal, B, 2010-08-17 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Removal of the second glucose by glucosidase II
output	[SimpleEntity:113780] Glc [endoplasmic reticulum lumen] [Complex:532672] unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1 [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:901082] MLEC [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:901006] Binding of Malectin [Homo sapiens] [Reaction:532678] Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105409] R-HSA-532667.2
summation	[Summation:532684] A second glucose is removed from the N-linked glycan. The re...
(hasEvent)	[Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle [Homo sapiens]
(precedingEvent)	[Reaction:535717] Binding of calnexin/calreticulin to the unfolded protein [Homo sapiens]
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No pathways have been reviewed or authored by Removal of the second glucose by glucosidase II (532667)