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Details on Person HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
| Class:Id | LiteratureReference:5324655 |
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| _displayName | HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates |
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| _timestamp | 2014-02-17 18:37:07 |
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| author | [Person:5324656] Boyault, Cyril
[Person:3927990] Zhang, Yu
[Person:5324679] Fritah, Sabrina
[Person:5324658] Caron, Cécile
[Person:5324636] Gilquin, Benoit
[Person:5324674] Kwon, So Hee
[Person:5324671] Garrido, Carmen
[Person:5324630] Yao, Tso-Pang
[Person:4793666] Vourc'h, Claire
[Person:5324646] Matthias, Patrick
[Person:4793909] Khochbin, Saadi |
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| created | [InstanceEdit:5324634] Shamovsky, V, 2014-02-17 |
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| journal | Genes Dev. |
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| pages | 2172-81 |
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| pubMedIdentifier | 17785525 |
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| title | HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates |
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| volume | 21 |
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| year | 2007 |
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| (literatureReference) | [CatalystActivityReference:9643604] misfolded protein binding activity of HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
[Complex:5324663] HDAC6:VCP:protein aggregates [cytosol] [Homo sapiens]
[Complex:5324677] HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] [Homo sapiens]
[Reaction:5324632] Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates [Homo sapiens]
[Reaction:9646345] Ubiquitin binds Vcp:Hdac6:Hsp90:Hsf1 [Mus musculus]
[Reaction:9646347] PolyUb-misfolded proteins bind VCP:HDAC6:HSP90:HSF1 [Homo sapiens]
[Reaction:9646354] PolyUb-Misfolded Proteins:HDAC6 dissociate from complex [Homo sapiens]
[Reaction:9646359] PolyUb-Misfolded Proteins:Hdac6 dissociate from complex [Mus musculus]
[Summation:4793891] In the absence of stress HSF1 is predominantly monomeric and...
[Summation:5324698] Proteotoxic stress results in an accumulation of misfolded p... |
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