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Details on Person Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
| Class:Id | LiteratureReference:532191 |
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| _displayName | Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb |
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| _timestamp | 2010-02-26 09:52:10 |
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| author | [Person:199852] Tee, AR
[Person:199822] Manning, BD
[Person:205127] Roux, PP
[Person:140008] Cantley, Lewis C
[Person:199307] Blenis, J |
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| created | [InstanceEdit:532190] Jassal, B, 2010-02-26 |
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| journal | Curr Biol |
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| pages | 1259-68 |
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| pubMedIdentifier | 12906785 |
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| title | Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb |
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| volume | 13 |
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| year | 2003 |
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| (literatureReference) | [Reaction:380979] RHEB in mTORC1:RHEB:GTP hydrolyses GTP [Homo sapiens]
[Reaction:9646464] RHEB:GTP hydrolyzes GTP [Homo sapiens]
[RegulationReference:9647720] Positive regulation by 'v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP:mTORC1:RHEB:GTP:TSC [lysosomal membrane]' Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb |
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