Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q9NYP8 EPCIP

Class:IdReferenceGeneProduct:53120
_chainChangeLogsignal peptide:1-19 added on Fri February 6 2015;chain:20-219 added on Fri February 6 2015
_displayNameUniProt:Q9NYP8 EPCIP
_timestamp2025-08-15 22:17:45
chainsignal peptide:1-19
chain:20-219
checksum44D0B404ECDD88B1
commentFUNCTION Likely to be involved with PKD1 in the detection, sequestration and exocytosis of senescent mitochondria.SUBUNIT Homooligomer (PubMed:37681898). Interacts with PKD1 (via the PKD repeats in the N-terminal extracellular region); the interaction is not dependent on N-glycosylation of either protein (PubMed:37681898).INTERACTION Detected on migrasomes and on extracellular exosomes in blood and urine.TISSUE SPECIFICITY Detected in the kidney and in the endothelium of large blood vessels (at protein level).PTM N-glycosylated.SIMILARITY Belongs to the EPCIP family.
descriptionrecommendedName: fullName evidence="5"Exosomal polycystin-1-interacting protein alternativeName: B37 alternativeName: fullName evidence="3"Polycystin-1-interacting protein 1
geneNameEPCIP
C21orf120
C21orf62
CU062
identifierQ9NYP8
isSequenceChangedFALSE
keywordGlycoprotein
Reference proteome
Secreted
Signal
modified[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09
[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:8987656] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9773244] Weiser, Joel
[InstanceEdit:9796771] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9862192] Weiser, Joel, 2024-02-26
[InstanceEdit:9909836] Weiser, Joel, 2024-05-14
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
[InstanceEdit:9939033] Weiser, Joel, 2025-02-21
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
nameEPCIP
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9004060] ENSEMBL:ENSG00000205929 EPCIP [Homo sapiens]
secondaryIdentifierEPCIP_HUMAN
A8K4L8
sequenceLength219
species[Species:48887] Homo sapiens
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No pathways have been reviewed or authored by UniProt:Q9NYP8 EPCIP (53120)