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Details on Person UniProt:Q9H8E8 KAT14
| Class:Id | ReferenceGeneProduct:52834 |
|---|---|
| _chainChangeLog | chain:1-782 added on Fri February 6 2015 |
| _displayName | UniProt:Q9H8E8 KAT14 |
| _timestamp | 2024-11-03 20:09:30 |
| chain | chain:1-782 |
| checksum | E84FAEF06412EA77 |
| comment | FUNCTION Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.SUBUNIT Interacts with the LIM 1 domain of CSRP2. Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, MBIP and WDR5.INTERACTION Mainly nuclear.ALTERNATIVE PRODUCTS Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung.MISCELLANEOUS May be due to an intron retention. |
| description | recommendedName: Cysteine-rich protein 2-binding protein shortName: CSRP2-binding protein alternativeName: ADA2A-containing complex subunit 2 shortName: ATAC2 alternativeName: CRP2-binding partner shortName: CRP2BP alternativeName: fullName evidence="11"Lysine acetyltransferase 14 |
| geneName | KAT14 CSRP2BP |
| identifier | Q9H8E8 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Cytoplasm Nucleus Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | KAT14 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9001100] ENSEMBL:ENSG00000149474 KAT14 [Homo sapiens] |
| secondaryIdentifier | CSR2B_HUMAN A2A2I5 Q96GW6 Q96IH3 Q9HBF0 Q9UIY5 |
| sequenceLength | 782 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:145962] UniProt:Q9H8E8-2 KAT14 [Homo sapiens] [ReferenceIsoform:414326] UniProt:Q9H8E8-1 KAT14 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:3301917] KAT14 [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q9H8E8 KAT14 (52834)
