Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P06850 CRH
| Class:Id | ReferenceGeneProduct:52788 |
|---|---|
| _chainChangeLog | signal peptide:1-24 added on Fri February 6 2015;propeptide:25-153 added on Fri February 6 2015;peptide:154-194 added on Fri February 6 2015 |
| _displayName | UniProt:P06850 CRH |
| _timestamp | 2024-11-03 19:45:15 |
| chain | signal peptide:1-24 propeptide:25-153 peptide:154-194 |
| checksum | 0CCDFF05BE364E92 |
| comment | FUNCTION Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).SUBUNIT Interacts (via C-terminus) with CRFR1 (via N-terminal extracellular domain).INTERACTION Produced by the hypothalamus and placenta.SIMILARITY Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.ONLINE INFORMATION Corticotropin-releasing hormone entry |
| description | recommendedName: Corticoliberin alternativeName: Corticotropin-releasing factor shortName: CRF alternativeName: Corticotropin-releasing hormone |
| geneName | CRH |
| identifier | P06850 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Proteomics identification Reference proteome Secreted Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CRH |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002287] ENSEMBL:ENSG00000147571 CRH [Homo sapiens] |
| secondaryIdentifier | CRF_HUMAN B3KQS4 |
| sequenceLength | 196 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:420146] CRH [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P06850 CRH (52788)
