Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person PI(4,5)P2 [cytoplasm]

Class:IdSimpleEntity:5277642
_displayNamePI(4,5)P2 [cytoplasm]
_timestamp2022-01-05 20:15:35
compartment[Compartment:459] cytoplasm
created[InstanceEdit:5323153] Preece, Justin, 2014-02-14
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9026179] D'Eustachio, Peter, 2017-10-17
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
[InstanceEdit:9760900] D'Eustachio, Peter, 2022-01-05
[InstanceEdit:9989189] Weiser, Joel, 2026-05-17
namePI(4,5)P2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-)
phys-ent-participant34084
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
phys-ent-participant105820
phys-ent-participant105769
phys-ent-participant105777
phys-ent-participant105822
phys-ent-participant105795
phys-ent-participant105836
phys-ent-participant105834
phys-ent-participant105803
phys-ent-participant50312
phys-ent-participant50777
phys-ent-participant32527
phys-ent-participant98428
phys-ent-participant105164
phys-ent-participant59073
referenceEntity[ReferenceMolecule:9760917] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) [ChEBI:58456]
stableIdentifier[StableIdentifier:8890842] R-ALL-5277642.1
(input)[Reaction:1120611] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase [Oryza sativa]
[Reaction:5269346] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+H2O->1,2-diacylglycerol+D-myo-inositol (1,4,5)-trisphosphate+H+ [Arabidopsis thaliana]
[Reaction:5269916] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+H2O->1,2-diacylglycerol+D-myo-inositol (1,4,5)-trisphosphate+H+ [Arabidopsis thaliana]
[Reaction:5269926] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+ATP->1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate+ADP+H+ [Arabidopsis thaliana]
[Reaction:5271048] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+H2O->1-phosphatidyl-1D-myo-inositol 4-phosphate+phosphate [Arabidopsis thaliana]
[Reaction:5271425] 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+H2O->1,2-diacylglycerol+D-myo-inositol (1,4,5)-trisphosphate+H+ [Arabidopsis thaliana]
(output)[Reaction:1120829] 1-phosphatidylinositol-5-phosphate 4-kinase [Oryza sativa]
[Reaction:1121308] 1-phosphatidylinositol-4-phosphate kinase [Oryza sativa]
[Reaction:5269350] 1-phosphatidyl-1D-myo-inositol 5-phosphate+ATP->1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+ADP+H+ [Arabidopsis thaliana]
[Reaction:5269924] 1-phosphatidyl-1D-myo-inositol 4-phosphate+ATP->1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+ADP+H+ [Arabidopsis thaliana]
[Reaction:5270495] 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate+H2O->1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate+phosphate [Arabidopsis thaliana]
(regulator)[PositiveRegulation:5264004] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264007] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264014] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264015] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264018] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264019] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264023] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
[PositiveRegulation:5264026] Positive regulation by 'PI(4,5)P2 [cytoplasm]'
(replacementInstances)[_Deleted:9026182] Deletion of instance: 1131191
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No pathways have been reviewed or authored by PI(4,5)P2 [cytoplasm] (5277642)