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Details on Person H2O+NAD++succinate semialdehyde->H++NADH+succinate

Class:Id	Reaction:5269270
_displayName	H2O+NAD++succinate semialdehyde->H++NADH+succinate
_doRelease	FALSE
_timestamp	2018-04-06 20:25:57
catalystActivity	[CatalystActivity:5265036] succinate-semialdehyde dehydrogenase (NAD+) activity of succinate-semialdehyde dehydrogenase (AT1G79440) [cytoplasm]
catalystActivityReference	[CatalystActivityReference:9643986] succinate-semialdehyde dehydrogenase (NAD+) activity of succinate-semialdehyde dehydrogenase (AT1G79440) [cytoplasm] Mitochondrial succinic-semialdehyde dehydrogenase of the gamma-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants
compartment	[Compartment:459] cytoplasm
created	[InstanceEdit:5323153] Preece, Justin, 2014-02-14
crossReference	[DatabaseIdentifier:5297589] AraCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN [DatabaseIdentifier:5297590] PIR:A55773 [DatabaseIdentifier:5297591] PIR:I61704 [DatabaseIdentifier:5297592] KEGG:R00713 [DatabaseIdentifier:5297587] UniProt:P51649 [DatabaseIdentifier:5297588] UniProt:P51650 [DatabaseIdentifier:5305748] EC-NUMBER:1.2.1.24
input	[SimpleEntity:5278291] H2O [cytoplasm] [SimpleEntity:1132064] NAD+ [cytoplasm] [SimpleEntity:1131780] SUCCSA [cytoplasm]
modified	[InstanceEdit:5622182] Amarasinghe, Vindhya, 2014-09-11 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9605047] D'Eustachio, Peter, 2018-04-06 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9643047] Wu, G, 2019-04-04
name	H2O+NAD++succinate semialdehyde->H++NADH+succinate SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN succinate semialdehyde dehydrogenase succinic semialdehyde dehydrogenase succinyl semialdehyde dehydrogenase biochemicalReaction71707
output	[SimpleEntity:1132304] H+ [cytoplasm] [SimpleEntity:1130844] NADH [cytoplasm] [SimpleEntity:5278787] SUCCA [cytoplasm] [SimpleEntity:1132304] H+ [cytoplasm]
precedingEvent	[Reaction:5269269] 2-oxoglutarate+4-aminobutanoate->L-glutamate+succinate semialdehyde [Arabidopsis thaliana] [Reaction:5270149] H++L-glutamate->CO2+4-aminobutanoate [Arabidopsis thaliana] [Reaction:5269271] 4-aminobutanoate+pyruvate->succinate semialdehyde+L-alanine [Arabidopsis thaliana] [Reaction:5270149] H++L-glutamate->CO2+4-aminobutanoate [Arabidopsis thaliana] [Reaction:5269271] 4-aminobutanoate+pyruvate->succinate semialdehyde+L-alanine [Arabidopsis thaliana] [Reaction:5270149] H++L-glutamate->CO2+4-aminobutanoate [Arabidopsis thaliana] [Reaction:5269269] 2-oxoglutarate+4-aminobutanoate->L-glutamate+succinate semialdehyde [Arabidopsis thaliana] [Reaction:5270149] H++L-glutamate->CO2+4-aminobutanoate [Arabidopsis thaliana]
regulatedBy	[NegativeRegulation:5263965] Negative regulation by 'ADP [cytoplasm]' [NegativeRegulation:5263966] Negative regulation by 'p-pyridoxal [cytoplasm]' [NegativeRegulation:5263967] Negative regulation by 'NADH [cytoplasm]' [NegativeRegulation:5263968] Negative regulation by 'ATP [cytoplasm]' [NegativeRegulation:5263970] Negative regulation by 'adenosine 5'-monophosphate [cytoplasm]'
regulationReference	[RegulationReference:9641356] Negative regulation by 'ADP [cytoplasm]' Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides [RegulationReference:9641498] Negative regulation by 'ATP [cytoplasm]' Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides [RegulationReference:9642285] Negative regulation by 'NADH [cytoplasm]' Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides [RegulationReference:9642425] Negative regulation by 'p-pyridoxal [cytoplasm]' Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides [RegulationReference:9642448] Negative regulation by 'adenosine 5'-monophosphate [cytoplasm]' Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides
species	[Species:170905] Arabidopsis thaliana
stableIdentifier	[StableIdentifier:8918403] R-ATH-5269270.1
(hasEvent)	[Pathway:5268036] 4-aminobutyrate degradation I [Arabidopsis thaliana] [Pathway:5268037] 4-aminobutyrate degradation IV [Arabidopsis thaliana] [Pathway:5268056] glutamate degradation IV [Arabidopsis thaliana]
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No pathways have been reviewed or authored by H2O+NAD++succinate semialdehyde->H++NADH+succinate (5269270)