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Details on Person (2R,3S)-3-isopropylmalate+NAD+->(2S)-2-isopropyl-3-oxosuccinate+NADH+H+
Class:Id Reaction:5268645
_displayName (2R,3S)-3-isopropylmalate+NAD+->(2S)-2-isopropyl-3-oxosuccinate+NADH+H+
_doRelease FALSE
_timestamp 2018-04-06 21:39:20
catalystActivity [CatalystActivity:5264513] 3-isopropylmalate dehydrogenase activity of 3-isopropylmalate dehydrogenase [cytoplasm]
compartment [Compartment:459] cytoplasm
created [InstanceEdit:5323153] Preece, Justin, 2014-02-14
crossReference [DatabaseIdentifier:5294025] AraCyc:3-ISOPROPYLMALDEHYDROG-RXN [DatabaseIdentifier:5294026] PIR:T46607 [DatabaseIdentifier:5294027] PIR:T43407 [DatabaseIdentifier:5294028] PIR:T31128 [DatabaseIdentifier:5294029] PIR:T29052 [DatabaseIdentifier:5294030] PIR:S75467 [DatabaseIdentifier:5294017] PIR:S72210 [DatabaseIdentifier:5294018] PIR:S72209 [DatabaseIdentifier:5294019] PIR:S55845 [DatabaseIdentifier:5294020] PIR:S50698 [DatabaseIdentifier:5294021] PIR:S48228 [DatabaseIdentifier:5294022] PIR:S48227 [DatabaseIdentifier:5294023] PIR:S48226 [DatabaseIdentifier:5294024] PIR:S48225 [DatabaseIdentifier:5294061] PIR:S43888 [DatabaseIdentifier:5294060] PIR:S43454 [DatabaseIdentifier:5294059] PIR:S35133 [DatabaseIdentifier:5294058] PIR:S32969 [DatabaseIdentifier:5294065] PIR:S30897 [DatabaseIdentifier:5294064] PIR:S25369 [DatabaseIdentifier:5294063] PIR:S20606 [DatabaseIdentifier:5294062] PIR:S20510 [DatabaseIdentifier:5294053] PIR:JX0286 [DatabaseIdentifier:5294052] PIR:I40235 [DatabaseIdentifier:5294051] PIR:I40226 [DatabaseIdentifier:5294050] PIR:F64106 [DatabaseIdentifier:5294057] PIR:E81836 [DatabaseIdentifier:5294056] PIR:DETWIT [DatabaseIdentifier:5294055] PIR:DEBYI [DatabaseIdentifier:5294054] PIR:DEBSIC [DatabaseIdentifier:5294044] PIR:C70322 [DatabaseIdentifier:5294045] PIR:B86777 [DatabaseIdentifier:5294042] PIR:B81270 [DatabaseIdentifier:5294043] PIR:A64729 [DatabaseIdentifier:5294048] PIR:A47620 [DatabaseIdentifier:5294049] PIR:A44851 [DatabaseIdentifier:5294046] PIR:A43324 [DatabaseIdentifier:5294047] PIR:A26522 [DatabaseIdentifier:5294041] PIR:A26447
input [SimpleEntity:5279671] (2R,3S)-3-isopropylmalate [cytoplasm] [SimpleEntity:1132064] NAD+ [cytoplasm]
modified [InstanceEdit:5679620] Amarasinghe, Vindhya, 2015-03-04 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9605079] D'Eustachio, Peter, 2018-04-06
name (2R,3S)-3-isopropylmalate+NAD+->(2S)-2-isopropyl-3-oxosuccinate+NADH+H+ 3-isopropylmalate dehydrogenase Beta-IPM dehydrogenase IMDH Beta-isopropylmalate dehydrogenase β-isopropylmalate dehydrogenase β-IPM dehydrogenase biochemicalReaction33013
output [SimpleEntity:5279669] (2S)-2-isopropyl-3-oxosuccinate [cytoplasm] [SimpleEntity:1130844] NADH [cytoplasm] [SimpleEntity:1132304] H+ [cytoplasm]
precedingEvent
species [Species:170905] Arabidopsis thaliana
stableIdentifier [StableIdentifier:8888239] R-ATH-5268645.1
(hasEvent) [Pathway:5267639] leucine biosynthesis [Arabidopsis thaliana] [Pathway:5268148] superpathway of leucine, valine, and isoleucine biosynthesis [Arabidopsis thaliana]
(precedingEvent) [Reaction:5268648] H++(2S)-2-isopropyl-3-oxosuccinate->4-methyl-2-oxopentanoate+CO2 [Arabidopsis thaliana]
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No pathways have been reviewed or authored by (2R,3S)-3-isopropylmalate+NAD+->(2S)-2-isopropyl-3-oxosuccinate+NADH+H+ (5268645)