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Details on Person L-aspartate+ATP->L-aspartyl-4-phosphate+ADP

Class:Id	Reaction:5268617
_displayName	L-aspartate+ATP->L-aspartyl-4-phosphate+ADP
_doRelease	FALSE
_timestamp	2018-04-06 21:25:48
catalystActivity	[CatalystActivity:5264480] aspartate kinase activity of aspartate kinase [cytoplasm]
compartment	[Compartment:459] cytoplasm
created	[InstanceEdit:5323153] Preece, Justin, 2014-02-14
crossReference	[DatabaseIdentifier:5293807] AraCyc:ASPARTATEKIN-RXN [DatabaseIdentifier:5293805] PIR:T06246 [DatabaseIdentifier:5293806] PIR:T06242 [DatabaseIdentifier:5293803] PIR:T04752 [DatabaseIdentifier:5293804] PIR:T03589 [DatabaseIdentifier:5293801] PIR:T02954 [DatabaseIdentifier:5293802] PIR:T02953 [DatabaseIdentifier:5293799] PIR:S46497 [DatabaseIdentifier:5293800] PIR:S42425 [DatabaseIdentifier:5293797] PIR:S42422 [DatabaseIdentifier:5293798] PIR:S35160 [DatabaseIdentifier:5293860] PIR:S15277 [DatabaseIdentifier:5293859] PIR:S15276 [DatabaseIdentifier:5293862] PIR:KIECD3 [DatabaseIdentifier:5293861] PIR:KIBYD [DatabaseIdentifier:5293864] PIR:JC4640 [DatabaseIdentifier:5293863] PIR:H81865 [DatabaseIdentifier:5293866] PIR:G84952 [DatabaseIdentifier:5293865] PIR:E81405 [DatabaseIdentifier:5293852] PIR:DEECK2 [DatabaseIdentifier:5293851] PIR:DEECK [DatabaseIdentifier:5293854] PIR:C64371 [DatabaseIdentifier:5293853] PIR:C46665 [DatabaseIdentifier:5293856] PIR:B47594 [DatabaseIdentifier:5293855] PIR:B47057 [DatabaseIdentifier:5293858] PIR:A64048 [DatabaseIdentifier:5293857] PIR:A48946 [DatabaseIdentifier:5293849] PIR:A47594 [DatabaseIdentifier:5293850] PIR:A29314 [DatabaseIdentifier:5305204] EC-NUMBER:2.7.2.4
input	[SimpleEntity:1130556] L-Asp [cytoplasm] [SimpleEntity:1131543] ATP [cytoplasm]
modified	[InstanceEdit:5627455] Amarasinghe, Vindhya, 2014-10-18 [InstanceEdit:5694756] Amarasinghe, Vindhya, 2015-05-23 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9605077] D'Eustachio, Peter, 2018-04-06 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04
name	L-aspartate+ATP->L-aspartyl-4-phosphate+ADP ASPARTATEKIN-RXN Aspartokinase biochemicalReaction24860
output	[SimpleEntity:5279589] L-aspartyl-4-phosphate [cytoplasm] [SimpleEntity:1131354] ADP [cytoplasm]
precedingEvent	[Reaction:5423130] oxaloacetate+L-glutamate->L-aspartate+2-oxoglutarate [Arabidopsis thaliana]
regulatedBy	[PositiveRegulation:5264098] Positive regulation by 'L-Ala [cytoplasm]' [PositiveRegulation:5264099] Positive regulation by 'L-isoleucine [cytoplasm]' [PositiveRegulation:5264100] Positive regulation by 'L-Cys [cytoplasm]' [PositiveRegulation:5264101] Positive regulation by 'L-leucine [cytoplasm]' [PositiveRegulation:5264102] Positive regulation by 'L-valine [cytoplasm]' [PositiveRegulation:5264104] Positive regulation by 'L-Ser [cytoplasm]'
regulationReference	[RegulationReference:9641303] Positive regulation by 'L-isoleucine [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity [RegulationReference:9641372] Positive regulation by 'L-Ala [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity [RegulationReference:9641482] Positive regulation by 'L-Cys [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity [RegulationReference:9641946] Positive regulation by 'L-Ser [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity [RegulationReference:9642255] Positive regulation by 'L-valine [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity [RegulationReference:9642450] Positive regulation by 'L-leucine [cytoplasm]' Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity
revised	[InstanceEdit:5627454] Amarasinghe, Vindhya, 2014-06-12
species	[Species:170905] Arabidopsis thaliana
stableIdentifier	[StableIdentifier:8922378] R-ATH-5268617.1
summation	[Summation:5694764] aspartate kinase is regulated by isoleucine
(hasEvent)	[Pathway:5267638] lysine biosynthesis VI [Arabidopsis thaliana] [Pathway:5267645] isoleucine biosynthesis I [Arabidopsis thaliana] [Pathway:5267664] homoserine biosynthesis [Arabidopsis thaliana] [Pathway:5267685] threonine biosynthesis [Arabidopsis thaliana] [Pathway:5268143] superpathway of lysine, threonine and methionine biosynthesis II [Arabidopsis thaliana]
(precedingEvent)	[Reaction:5268621] NADP++phosphate+L-aspartate-semialdehyde->H++NADPH+L-aspartyl-4-phosphate [Arabidopsis thaliana] [Reaction:5627463] H++NADPH+L-aspartyl-4-phosphate->NADP++phosphate+L-aspartate-semialdehyde [Arabidopsis thaliana]
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No pathways have been reviewed or authored by L-aspartate+ATP->L-aspartyl-4-phosphate+ADP (5268617)