Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person MeSeOH is reduced to MeSeH by TXNRD1

Class:Id	Reaction:5263614
_displayName	MeSeOH is reduced to MeSeH by TXNRD1
_doRelease	TRUE
_timestamp	2015-11-20 15:08:02
authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359073] methylselenol reductase activity of TNXRD1:FAD dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5263615] Williams, MG, 2014-02-12
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
input	[SimpleEntity:5357663] MeSeOH [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5359370] Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium
modified	[InstanceEdit:5359121] Williams, MG, 2014-04-08 [InstanceEdit:5359393] Williams, MG, 2014-04-09 [InstanceEdit:5422928] Williams, MG, 2014-05-06 [InstanceEdit:5422935] Williams, MG, 2014-05-06 [InstanceEdit:6793107] D'Eustachio, Peter, 2015-08-30 [InstanceEdit:6793354] D'Eustachio, Peter, 2015-09-01 [InstanceEdit:6804181] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:6804182] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MeSeOH is reduced to MeSeH by TXNRD1
output	[SimpleEntity:5357669] MeSeH [cytosol] [SimpleEntity:29366] NADP+ [cytosol] [SimpleEntity:29356] H2O [cytosol]
precedingEvent	[Reaction:5263616] MeSeO2H is reduced to MeSeOH by TXNRD1 [Homo sapiens] [BlackBoxEvent:5333612] MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812347] R-HSA-5263614.2
summation	[Summation:5422882] Thioredoxin reductase 1 (TXNRD1) homodimer is involved in th...
(hasEvent)	[Pathway:5263617] Metabolism of ingested MeSeO2H into MeSeH [Homo sapiens]
(precedingEvent)	[Reaction:2408530] MeSeH is hydrolysed to H2Se by methylselenol demethylase [Homo sapiens] [Reaction:2408541] MeSeH is methylated to Me2Se by MeSeH methyltransferase [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by MeSeOH is reduced to MeSeH by TXNRD1 (5263614)