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Details on Person UniProt:Q68D85 NCR3LG1
| Class:Id | ReferenceGeneProduct:525926 |
|---|---|
| _chainChangeLog | signal peptide:1-24 added on Fri February 6 2015;chain:25-454 added on Fri February 6 2015 |
| _displayName | UniProt:Q68D85 NCR3LG1 |
| _timestamp | 2024-11-03 20:11:04 |
| chain | signal peptide:1-24 chain:25-454 |
| checksum | 433CE0B0EE0A4470 |
| comment | FUNCTION Triggers NCR3-dependent natural killer cell activation.SUBUNIT Monomer. Interacts specifically with NCR3, but not with other natural killer cell-activating receptors, including NCR1, NCR2 and KLRK1.INTERACTION Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level).DOMAIN The C-terminal part is similar to retroviral Gag protein. This putative protein seems to be the result of a fusion between an Ig-like domain-containing protein and a ERV.SEQUENCE CAUTION Extended N-terminus. |
| created | [InstanceEdit:525883] Kanapin, AA |
| description | recommendedName: Natural cytotoxicity triggering receptor 3 ligand 1 alternativeName: B7 homolog 6 shortName: B7-H6 |
| geneName | NCR3LG1 B7H6 |
| identifier | Q68D85 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Proteomics identification Reference proteome Repeat Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | NCR3LG1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8994995] ENSEMBL:ENSG00000188211 NCR3LG1 [Homo sapiens] |
| secondaryIdentifier | NR3L1_HUMAN Q7Z3M6 |
| sequenceLength | 454 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5683240] NCR3LG1 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q68D85 NCR3LG1 (525926)
