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Details on Person ERCC6 recruits KAT2B and RNA Pol I to rRNA promoter

Class:Id	Reaction:5250632
_displayName	ERCC6 recruits KAT2B and RNA Pol I to rRNA promoter
_timestamp	2016-07-15 23:50:29
authored	[InstanceEdit:5250518] May, B, 2014-01-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5250620] May, B, 2014-01-29
edited	[InstanceEdit:5250518] May, B, 2014-01-25
input	[Complex:5250633] rDNA promoter:UBTF:ERCC6:NuRD [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:352430] KAT2B [nucleoplasm] [Homo sapiens] [Complex:73859] RNA Polymerase I Holoenzyme [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5250647] The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation [LiteratureReference:5096460] The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions
modified	[InstanceEdit:5250950] May, B, 2014-01-31 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	ERCC6 recruits KAT2B and RNA Pol I to rRNA promoter
output	[Complex:5250656] rDNA promoter:UBTF:ERCC6:KAT2B:RNA Pol I [nucleoplasm] [Homo sapiens] [Complex:4657018] NuRD complex [nucleoplasm] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8921153] R-HSA-5250632.1
summation	[Summation:5250931] A poised rRNA promoter is bound by ERCC6 (CSB), UBTF (UBF), ...
(hasEvent)	[Pathway:5250621] ERCC6 (CSB) and KAT2B (PCAF) positively regulate rRNA expression [Homo sapiens]
(precedingEvent)	[Reaction:5250657] KAT2B acetylates histones in rDNA [Homo sapiens]
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No pathways have been reviewed or authored by ERCC6 recruits KAT2B and RNA Pol I to rRNA promoter (5250632)