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Query author contributions in Reactome

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Details on Person Slc1a1 encodes an excitatory amino-acid carrier 1 (Eaac1 aka...

Class:IdSummation:5250236
_displayNameSlc1a1 encodes an excitatory amino-acid carrier 1 (Eaac1 aka...
_timestamp2014-01-24 12:27:20
created[InstanceEdit:5250224] Jassal, Bijay, 2014-01-24
textSlc1a1 encodes an excitatory amino-acid carrier 1 (Eaac1 aka GTRAP3-18) and is abundant particularly in brain but also in liver, muscle, ovary, testis and in retinoblastoma cell lines. In the kidney, Eaac1 is present at apical membranes of proximal tubes. PRA1 family protein 3 (Arl6ip5 aka ADP-ribosylation factor-like protein 6-interacting protein 5) is a microtuble-associated protein that is able to regulate intracellular concentrations of glutamate as well as tuarine. It negatively regulates Eaac1 by decreasing its affinity for glutamate (L-Glu) (Lin et al. 2001).
(summation)[Reaction:5250226] Eaac1 exchanges L-Glu, H+ and 3Na+ for K+ [Rattus norvegicus]
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