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Details on Person Eaac1 exchanges L-Glu, H+ and 3Na+ for K+

Class:IdReaction:5250226
_displayNameEaac1 exchanges L-Glu, H+ and 3Na+ for K+
_doReleaseTRUE
_timestamp2016-07-15 23:49:11
authored[InstanceEdit:5250224] Jassal, Bijay, 2014-01-24
catalystActivity[CatalystActivity:5250234] high-affinity L-glutamate transmembrane transporter activity of Eaac1 [plasma membrane]
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
[Compartment:984] extracellular region
created[InstanceEdit:5250224] Jassal, Bijay, 2014-01-24
edited[InstanceEdit:5250224] Jassal, Bijay, 2014-01-24
input[SimpleEntity:351626] H+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:29804] K+ [cytosol]
[SimpleEntity:210382] L-Glu [extracellular region]
literatureReference[LiteratureReference:5250235] Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18
modified[InstanceEdit:428053] Jassal, Bijay, 2009-06-30
[InstanceEdit:433652] Jassal, Bijay, 2009-08-24
[InstanceEdit:5250532] Jassal, Bijay, 2014-01-27
[InstanceEdit:5674394] Jassal, Bijay, 2015-02-12
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
nameEaac1 exchanges L-Glu, H+ and 3Na+ for K+
output[SimpleEntity:70106] H+ [cytosol]
[SimpleEntity:74126] K+ [extracellular region]
[SimpleEntity:83910] Na+ [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
[SimpleEntity:29404] L-Glu [cytosol]
regulatedBy[NegativeRegulation:5255422] Negative regulation by 'Arl6ip5 [cytosol]'
reviewed[InstanceEdit:5674208] D'Eustachio, Peter, 2015-02-11
species[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:8887842] R-RNO-5250226.1
summation[Summation:5250236] Slc1a1 encodes an excitatory amino-acid carrier 1 (Eaac1 aka...
(inferredFrom)[Reaction:5250230] SLC1A1 exchanges L-Glu, H+ and 3Na+ for K+ [Homo sapiens]
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