Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Hess, Jay L

Class:IdPerson:5244719
_displayNameHess, Jay L
_timestamp2014-01-20 17:23:00
created[InstanceEdit:5244704] Jupe, S, 2014-01-20
firstnameJay L
initialJL
surnameHess
(author)[LiteratureReference:5244699] Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
[LiteratureReference:5244752] MLL associates specifically with a subset of transcriptionally active target genes
[LiteratureReference:5669136] MLL targets SET domain methyltransferase activity to Hox gene promoters
[LiteratureReference:9036609] CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis
[LiteratureReference:9036612] MLL-ENL inhibits polycomb repressive complex 1 to achieve efficient transformation of hematopoietic cells
[LiteratureReference:9770968] Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
[LiteratureReference:9772522] Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia
[LiteratureReference:9772914] MLL core components give the green light to histone methylation
[LiteratureReference:9772970] Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
[LiteratureReference:9818944] Interaction of MLL amino terminal sequences with menin is required for transformation
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No pathways have been reviewed or authored by Hess, Jay L (5244719)