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Details on Person Coactivator-associated arginine methyltransferase 1 (CARM1, ...

Class:IdSummation:5229014
_displayNameCoactivator-associated arginine methyltransferase 1 (CARM1, ...
_timestamp2014-01-20 08:01:54
created[InstanceEdit:5229013] Jupe, S, 2014-01-15
literatureReference[LiteratureReference:5205841] Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter
[LiteratureReference:5205880] Methylation at arginine 17 of histone H3 is linked to gene activation
[LiteratureReference:5205811] Methylation of histone H3 by coactivator-associated arginine methyltransferase 1
modified[InstanceEdit:5205870] Jupe, S, 2013-12-06
[InstanceEdit:5228568] Jupe, S, 2014-01-14
[InstanceEdit:5229016] Jupe, S, 2014-01-15
[InstanceEdit:5244528] Jupe, S, 2014-01-20
textCoactivator-associated arginine methyltransferase 1 (CARM1, PRMT4) methylates histone H3 at arginine-18 (H3R17) (Ma et al. 2001, Bauer et al. 2002) and to a lesser extent arginine-27 (H3R26) (Schurter et al. 2001, Bauer et al. 2002). In vitro it can also methylate arginine-3, and one or more of four arginines (129/130/132/135) at the C-terminus (Schurter et al. 2001).
(summation)[Reaction:5229010] CARM1 methylates arginine-27 of histone H3 (H3R26) [Homo sapiens]
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