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Details on Person botB HC:LC dimer [extracellular region]

Class:Id	Complex:5228599
_displayName	botB HC:LC dimer [extracellular region]
_timestamp	2020-10-08 22:00:29
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:5228609] D'Eustachio, Peter, 2014-01-14
disease	[Disease:3632909] botulism
hasComponent	[EntityWithAccessionedSequence:181507] botB HC disulfide bonded [extracellular region] [Clostridium botulinum] [Complex:190022] botB LC:Zn2+ disulfide bonded [extracellular region] [Clostridium botulinum] [EntityWithAccessionedSequence:181565] botB LC disulfide bonded [extracellular region] [Clostridium botulinum] [SimpleEntity:158417] Zn2+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:181709] Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B
modified	[InstanceEdit:9704403] D'Eustachio, Peter, 2020-10-08
name	botB HC:LC dimer BoNT/B HC:LC dimer
species	[Species:168825] Clostridium botulinum
stableIdentifier	[StableIdentifier:5648403] R-CBO-5228599.2
(hasComponent)	[Complex:5228681] botB HC:LC dimer:NTNHA:HA [extracellular region] [Clostridium botulinum]
(input)	[Reaction:5244397] botB HC:LC binds SYT1 or 2 and GT1b on the target cell surface [Homo sapiens]
(output)	[BlackBoxEvent:5228940] Transcytosis and dissociation of botB:NTNHA:HA [Homo sapiens]
(replacementInstances)	[_Deleted:5251021] Deletion of instance: 181486
(updatedInstance)	[_UpdateTracker:9901878] Update Tracker - [Complex:5228599] botB HC:LC dimer [extracellular region] - v75:[addName, updateContainedComponent]
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No pathways have been reviewed or authored by botB HC:LC dimer [extracellular region] (5228599)