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Details on Person tetX LC:Zn2+ [cytosol]

Class:IdComplex:5228371
_displayNametetX LC:Zn2+ [cytosol]
_timestamp2020-10-08 22:01:43
compartment[Compartment:70101] cytosol
created[InstanceEdit:5228373] D'Eustachio, Peter, 2014-01-10
disease[Disease:5228387] tetanus
goCellularComponent[Compartment:436407] host cell cytosol
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:5228400] Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro-neuronal synapses, and its internalization is mediated by heavy chain
[LiteratureReference:5228377] Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc
modified[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9704403] D'Eustachio, Peter, 2020-10-08
[InstanceEdit:9715688] Shorser, Solomon, 2021-02-17
[InstanceEdit:9729976] Shorser, Solomon, 2021-05-05
[InstanceEdit:9750461] Weiser, JD, 2021-08-11
[InstanceEdit:9757984] Weiser, JD, 2021-11-08
[InstanceEdit:9767390] Wright, Adam, 2022-02-25
[InstanceEdit:9773515] Weiser, Joel, 2022-05-04
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9917728] Weiser, Joel, 2024-08-09
[InstanceEdit:9926726] Weiser, Joel, 2024-11-03
[InstanceEdit:9939161] Weiser, Joel, 2025-02-21
[InstanceEdit:9948552] Weiser, Joel, 2025-05-21
[InstanceEdit:9963749] Weiser, Joel, 2025-08-15
[InstanceEdit:9970792] Weiser, Joel, 2025-10-31
[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
[InstanceEdit:9989150] Weiser, Joel, 2026-05-15
nametetX LC:Zn2+
TeNT LC:Zn2+
species[Species:5228399] Clostridium tetani
stableIdentifier[StableIdentifier:5646154] R-CTE-5228371.20
(output)[BlackBoxEvent:5228406] tetX HC transports tetX LC from target cell endosome membrane into cytosol [Homo sapiens]
(physicalEntity)[CatalystActivity:5228363] metalloendopeptidase activity of tetX LC:Zn2+ [cytosol]
(updatedInstance)[_UpdateTracker:9901754] Update Tracker - [Complex:5228371] tetX LC:Zn2+ [cytosol] - v75:[addName]
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No pathways have been reviewed or authored by tetX LC:Zn2+ [cytosol] (5228371)