Query author contributions in Reactome
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Details on Person Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiqu...
| Class:Id | Summation:5226984 |
|---|---|
| _displayName | Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiqu... |
| _timestamp | 2014-03-21 13:43:58 |
| created | [InstanceEdit:5227003] Jassal, Bijay, 2014-01-09 |
| modified | [InstanceEdit:5357426] Jassal, B, 2014-03-21 |
| text | Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiquitously expressed, membrane-cytoskeletal protein that can promote the assembly of the spectrin-actin network. It is functional in a heterodimeric form, in complex with either a beta (ADD2 aka ADDB) (Khan et al. 2008) or a gamma (ADD3 aka ADDL) subunit (Citterio et al. 2003). Either complex is able to bind dematin (DMTN) (Azim et al. 1995), a membrane-cytoskeletal protein that can induce F-actin bundles formation and stabilization. It can also bind the erythrocyte membrane glucose transporter 1 (SLC2A1 aka GLUT1), and hence stabilise the spectrin-actin network to the erythrocytic plasma membrane (Khan et al. 2008). |
| (summation) | [Reaction:5226979] ADD1:ADD2 binds DMTN [Homo sapiens] |
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No pathways have been reviewed or authored by Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiqu... (5226984)
