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Details on Person ANKH transports PPi from cytosol to extracellular region

Class:Id	Reaction:5226964
_displayName	ANKH transports PPi from cytosol to extracellular region
_doRelease	TRUE
_timestamp	2015-03-04 04:03:03
authored	[InstanceEdit:5227003] Jassal, Bijay, 2014-01-09
catalystActivity	[CatalystActivity:5226932] phosphate transmembrane transporter activity of ANKH [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:5227003] Jassal, Bijay, 2014-01-09
edited	[InstanceEdit:5227003] Jassal, Bijay, 2014-01-09
input	[SimpleEntity:111294] PPi [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5226899] Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH [LiteratureReference:5226978] Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease [LiteratureReference:5226906] Mutations in ANKH cause chondrocalcinosis [LiteratureReference:5226995] Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK [LiteratureReference:5226912] Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia
modified	[InstanceEdit:5357426] Jassal, B, 2014-03-21 [InstanceEdit:5367033] Jassal, Bijay, 2014-04-25 [InstanceEdit:5674209] Jassal, Bijay, 2015-02-11 [InstanceEdit:5674394] Jassal, Bijay, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ANKH transports PPi from cytosol to extracellular region
output	[SimpleEntity:113542] PPi [extracellular region]
releaseDate	2015-03-19
reviewed	[InstanceEdit:5674208] D'Eustachio, Peter, 2015-02-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680039] R-HSA-5226964.2
summation	[Summation:5226910] Progressive ankylosis protein homolog (ANKH) is a putative t...
(hasEvent)	[Pathway:5223345] Miscellaneous transport and binding events [Homo sapiens]
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No pathways have been reviewed or authored by ANKH transports PPi from cytosol to extracellular region (5226964)