Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Putative adenosylhomocysteinase 2 (AHCYL1 aka adenosylhomocy...

Class:IdSummation:5226948
_displayNamePutative adenosylhomocysteinase 2 (AHCYL1 aka adenosylhomocy...
_timestamp2015-02-11 13:18:17
created[InstanceEdit:5227003] Jassal, Bijay, 2014-01-09
modified[InstanceEdit:5357426] Jassal, B, 2014-03-21
[InstanceEdit:5674209] Jassal, Bijay, 2015-02-11
textPutative adenosylhomocysteinase 2 (AHCYL1 aka adenosylhomocysteine hydrolase-like protein 1) (Dekker et al. 2002) possesses 50% homology to adenosylhomocysteine hydrolase (AHCY), an enzyme important for metabolizing S-adenosyl-l-homocysteine. AHCYL1 can bind to the inositol 1,4,5-trisphosphate receptor (ITPR1) tetramer, suggesting that AHCYL1 is involved in modulating intracellular calcium release (Cooper et al. 2006).
(summation)[Reaction:5226904] AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it [Homo sapiens]
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No pathways have been reviewed or authored by Putative adenosylhomocysteinase 2 (AHCYL1 aka adenosylhomocy... (5226948)