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Details on Person UniProt:O95484 CLDN9
| Class:Id | ReferenceGeneProduct:52248 |
|---|---|
| _chainChangeLog | chain:1-217 added on Fri February 6 2015 |
| _displayName | UniProt:O95484 CLDN9 |
| _timestamp | 2024-11-03 19:50:28 |
| chain | chain:1-217 |
| checksum | 0E49C5B5CB3AAC9C |
| comment | FUNCTION Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.FUNCTION (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.SUBUNIT Interacts with CLDN1, CD81 and OCLN (PubMed:20375010).INTERACTION Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the claudin family. |
| description | recommendedName: Claudin-9 |
| geneName | CLDN9 |
| identifier | O95484 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell junction Cell membrane Deafness Host cell receptor for virus entry Host-virus interaction Membrane Non-syndromic deafness Proteomics identification Receptor Reference proteome Tight junction Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CLDN9 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997075] ENSEMBL:ENSG00000213937 CLDN9 [Homo sapiens] |
| secondaryIdentifier | CLD9_HUMAN |
| sequenceLength | 217 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:420016] CLDN9 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:421271] CLDN9 [cell junction] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:O95484 CLDN9 (52248)
