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Details on Person PTK2beta binds alphaVbeta3

Class:Id	Reaction:5218836
_displayName	PTK2beta binds alphaVbeta3
_doRelease	TRUE
_timestamp	2017-10-23 12:23:51
authored	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5218840] Garapati, P V, 2013-12-19
edited	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
input	[EntityWithAccessionedSequence:390932] PTK2B [cytosol] [Homo sapiens] [Complex:5218779] VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5218592] Tyrosine phosphorylation of beta3 integrin provides a binding site for Pyk2
modified	[InstanceEdit:5228340] Jupe, S, 2014-01-10 [InstanceEdit:5228988] Garapati, P V, 2014-01-15 [InstanceEdit:5432676] Garapati, P V, 2014-05-12 [InstanceEdit:5490368] Garapati, P V, 2014-05-19 [InstanceEdit:9026708] Rothfels, Karen, 2017-10-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PTK2beta binds alphaVbeta3
output	[Complex:5218787] VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5218818] Integrin alphaVbeta3 binds p-6Y-VEGFR2 [Homo sapiens] [Reaction:4420117] VEGFR2 autophosphorylates [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5432673] Welsh, Michael, Berger, Philipp, Ballmer-Hofer, Kurt, 2014-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644592] R-HSA-5218836.3
summation	[Summation:5218513] Proline tyrosine kinase 2-beta (PTK2B), also known as cell a...
(hasEvent)	[Pathway:4420097] VEGFA-VEGFR2 Pathway [Homo sapiens]
(precedingEvent)	[Reaction:5218830] SRC-1 phosphorylates PTK2-beta [Homo sapiens]
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No pathways have been reviewed or authored by PTK2beta binds alphaVbeta3 (5218836)