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Details on Person PDK1 phosphorylates PKC

Class:Id	Reaction:5218821
_displayName	PDK1 phosphorylates PKC
_doRelease	TRUE
_timestamp	2014-11-20 02:38:41
authored	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
catalystActivity	[CatalystActivity:377328] protein serine/threonine kinase activity of PDPK1 [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5218840] Garapati, P V, 2013-12-19
edited	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
input	[SimpleEntity:113592] ATP [cytosol] [DefinedSet:5218761] PKCA,PKCB,PKCD,PKCZ [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4332315] Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) [LiteratureReference:5218368] PDK-1 and protein kinase C phosphorylation
modified	[InstanceEdit:5228340] Jupe, S, 2014-01-10 [InstanceEdit:5432676] Garapati, P V, 2014-05-12 [InstanceEdit:5490368] Garapati, P V, 2014-05-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PDK1 phosphorylates PKC
output	[SimpleEntity:29370] ADP [cytosol] [DefinedSet:5218754] p-PKCA,p-PKCB,p-PKCZ,p-PKCD [cytosol] [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5432673] Welsh, Michael, Berger, Philipp, Ballmer-Hofer, Kurt, 2014-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644471] R-HSA-5218821.2
summation	[Summation:5218409] Protein kinase C (PKC) activation enhances angiogenesis by p...
(hasEvent)	[Pathway:5218921] VEGFR2 mediated cell proliferation [Homo sapiens]
(precedingEvent)	[Reaction:5218805] PKC autophosphorylates [Homo sapiens]
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No pathways have been reviewed or authored by PDK1 phosphorylates PKC (5218821)