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Details on Person VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2

Class:Id	LiteratureReference:5218543
_displayName	VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
_timestamp	2013-12-19 16:35:46
author	[Person:5218461] Garrett, Tiana A [Person:5218372] Van Buul, Jaap D [Person:5218338] Burridge, Keith
created	[InstanceEdit:5218480] Garapati, P V, 2013-12-19
journal	Exp. Cell Res.
pages	3285-97
pubMedIdentifier	17686471
title	VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
volume	313
year	2007
(literatureReference)	[Summation:5218467] Following VEGF treatment, VAV2 phosphorylation on tyrosine 1... [Summation:5218570] PI3-kinase (PI3K) catalyzes the phosphorylation of inositol ... [Summation:9968085] SRC promotes RAC1 activation primarily through tyrosine p... [Summation:9970164] SRC-phosphorylated RAC1/CDC42 guanine nucleotide exchange... [Reaction:5218820] Src kinases phosphorylate VAV [Homo sapiens] [Reaction:5218850] VAV exchanges GTP for GDP on RAC1, activating it [Homo sapiens] [Reaction:8951586] p-VAV family:PIP3 binds RAC1:GDP [Homo sapiens] [BlackBoxEvent:9958892] SRC promotes RAC1 and CDC42 activation by phosphorylating RAC1 and CDC42 GEFs [Homo sapiens] [BlackBoxEvent:9970163] SRC-phosphorylated RAC1,(CDC42) GEFs activate RAC1,(CDC42) [Homo sapiens]
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