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Details on Person Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

Class:Id	LiteratureReference:5205696
_displayName	Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
_timestamp	2013-12-05 21:55:40
author	[Person:159839] Molloy, Sean S [Person:5205710] Bresnahan, Patricia A [Person:5205698] Leppla, Stephen H [Person:5205713] Klimpel, Kurt R [Person:159825] Thomas, Gary
created	[InstanceEdit:5205725] D'Eustachio, Peter, 2013-12-05
journal	J. Biol. Chem.
pages	16396-402
pubMedIdentifier	1644824
title	Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
volume	267
year	1992
(literatureReference)	[EntityWithAccessionedSequence:5205700] pagA(30-196) [extracellular region] [Bacillus anthracis] [EntityWithAccessionedSequence:5205715] pagA(197-794) [plasma membrane] [Bacillus anthracis] [EntityWithAccessionedSequence:5210910] PA63 [endosome membrane] [Bacillus anthracis] [Reaction:5210912] Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) [Homo sapiens] [Reaction:5210935] Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) [Homo sapiens]
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No pathways have been reviewed or authored by Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen (5205696)