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Details on Person PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
| Class:Id | LiteratureReference:5205666 |
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| _displayName | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin |
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| _timestamp | 2013-12-04 20:30:30 |
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| author | [Person:5205643] Narendra, Derek P
[Person:5205623] Jin, Seok Min
[Person:5205622] Tanaka, Atsushi
[Person:5205660] Suen, Der-Fen
[Person:5205631] Gautier, Clement A
[Person:5205645] Shen, Jie
[Person:5205640] Cookson, Mark R
[Person:141842] Youle, RJ |
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| created | [InstanceEdit:5205680] Gillespie, Marc E, 2013-12-04 |
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| journal | PLoS Biol. |
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| pages | e1000298 |
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| pubMedIdentifier | 20126261 |
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| title | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin |
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| volume | 8 |
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| year | 2010 |
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| (literatureReference) | [Reaction:5205661] Pink1 is recruited from the cytoplasm to the mitochondria [Homo sapiens]
[Reaction:5205672] Uncleaved Pink1 accumulates in damaged mitochondria [Homo sapiens]
[Reaction:5205681] Pink1 is cleaved on healthy mitochondria [Homo sapiens]
[BlackBoxEvent:9835009] PRKN binds p-S-Ub:MOM proteins [Homo sapiens]
[Reaction:9910581] Clone of 5205652 Pink1 recruits Parkin to the outer mitochondrial membrane, that is replaced by 9835009 [Homo sapiens]
[Summation:9839455] A loss in mitochondrial membrane potential leads to the PINK...
[Summation:9839893] The E3 ubiquitin protein ligase parkin (PRKN) translocates t... |
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