Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person On damaged mitochondria that have lost their membrane potent...

Class:IdSummation:5205629
_displayNameOn damaged mitochondria that have lost their membrane potent...
_timestamp2024-01-24 01:48:38
created[InstanceEdit:5205680] Gillespie, Marc E, 2013-12-04
modified[InstanceEdit:5633134] Gillespie, Marc E, 2014-10-30
[InstanceEdit:9859635] Shamovsky, Veronica, 2024-01-24
textOn damaged mitochondria that have lost their membrane potential, however, PINK1 cleavage is inhibited, leading to high PINK1 protein accumulation on the inner leaf of the mitochondrial outer membrane (MOM) of dysfunctional mitochondria. Full-length mitochondrial PINK1 is the active form in the PINK1/Parkin pathway.
(summation)[Reaction:5205672] Uncleaved Pink1 accumulates in damaged mitochondria [Homo sapiens]
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No pathways have been reviewed or authored by On damaged mitochondria that have lost their membrane potent... (5205629)