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Details on Person CDK1 phosphorylates LPIN

Class:IdReaction:5195402
_displayNameCDK1 phosphorylates LPIN
_doReleaseTRUE
_timestamp2022-02-08 22:02:03
authored[InstanceEdit:5251380] Orlic-Milacic, M, 2014-02-02
catalystActivity[CatalystActivity:174240] cyclin-dependent protein serine/threonine kinase activity of CCNB1:p-T161-CDK1 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5195403] Orlic-Milacic, M, 2013-12-02
edited[InstanceEdit:5251380] Orlic-Milacic, M, 2014-02-02
input[CandidateSet:4419925] LPIN [nuclear envelope] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:549166] Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2
[LiteratureReference:4419942] Phosphorylation of phosphatidate phosphatase regulates its membrane association and physiological functions in Saccharomyces cerevisiae: identification of SER(602), THR(723), AND SER(744) as the sites phosphorylated by CDC28 (CDK1)-encoded cyclin-dependent kinase
[LiteratureReference:4419941] A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase
modified[InstanceEdit:5205594] Orlic-Milacic, M, 2013-12-03
[InstanceEdit:5324615] Orlic-Milacic, M, 2014-02-17
[InstanceEdit:9032154] Orlic-Milacic, Marija, 2017-12-06
[InstanceEdit:9764059] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCDK1 phosphorylates LPIN
negativePrecedingEvent[NegativePrecedingEvent:9764057] Futile Cycle: CTDNEP1:CNEP1R1 dephosphorylates LPIN
output[SimpleEntity:113582] ADP [nucleoplasm]
[CandidateSet:4419938] p-S106-LPIN [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2014-03-12
reviewed[InstanceEdit:5324613] Gorjánácz, Mátyás, 2014-02-10
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5644872] R-HSA-5195402.4
summation[Summation:5205592] Lipins (LPIN1, LPIN2, LPIN3) possess several proline-directe...
(hasEvent)[Pathway:4419969] Depolymerization of the Nuclear Lamina [Homo sapiens]
(precedingEvent)[Reaction:4419948] CTDNEP1:CNEP1R1 dephosphorylates LPIN [Homo sapiens]
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No pathways have been reviewed or authored by CDK1 phosphorylates LPIN (5195402)