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Details on Person TLR2-1 : TLR1-2 heterodimer binds to its ligand

Class:Id	Reaction:517850
_displayName	TLR2-1 : TLR1-2 heterodimer binds to its ligand
_doRelease	TRUE
_timestamp	2010-12-02 14:38:31
authored	[InstanceEdit:517844] Shamovsky, V, 2010-02-20
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:517844] Shamovsky, V, 2010-02-20
edited	[InstanceEdit:994006] Shamovsky, V, 2010-11-05
input	[Complex:517845] TLR2-1 : TLR1-2 heteroodimer [plasma membrane] [Gallus gallus] [DefinedSet:517843] Ligand recognized by chicken TLR2-1 : TLR1-2 heterodimer [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:571250] Combinational recognition of bacterial lipoproteins and peptidoglycan by chicken Toll-like receptor 2 subfamily [LiteratureReference:571376] The central leucine-rich repeat region of chicken TLR16 dictates unique ligand specificity and species-specific interaction with TLR2
modified	[InstanceEdit:571377] Shamovsky, V, 2010-04-09 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:1094880] Shamovsky, V, 2010-11-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TLR2-1 : TLR1-2 heterodimer binds to its ligand
output	[Complex:517842] chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] [Gallus gallus]
releaseDate	2010-12-14
reviewed	[InstanceEdit:977269] D'Eustachio, P, 2010-10-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1105256] R-GGA-517850.2
summation	[Summation:571375] Higuchi et al. (2008) and Keestra et al. (2007) demonstrated...
(hasEvent)	[Pathway:517856] TLR2 subfamily cascade [Gallus gallus]
(precedingEvent)	[Reaction:433961] Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 [Gallus gallus]
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No pathways have been reviewed or authored by TLR2-1 : TLR1-2 heterodimer binds to its ligand (517850)