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Details on Person UniProt:P32320 CDA
| Class:Id | ReferenceGeneProduct:51784 |
|---|---|
| _chainChangeLog | chain:1-146 added on Sat February 7 2015 |
| _displayName | UniProt:P32320 CDA |
| _timestamp | 2025-02-21 18:55:00 |
| chain | chain:1-146 |
| checksum | AF33D09EE4E176B3 |
| comment | FUNCTION This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.CATALYTIC ACTIVITY cytidine + H2O + H(+) = uridine + NH4(+)CATALYTIC ACTIVITY 2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)COFACTOR Homotetramer.INTERACTION Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.SIMILARITY Belongs to the cytidine and deoxycytidylate deaminase family. |
| description | recommendedName: fullName evidence="7"Cytidine deaminase ecNumber evidence="4 6"3.5.4.5 alternativeName: Cytidine aminohydrolase |
| geneName | CDA CDD |
| identifier | P32320 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Hydrolase Metal-binding Proteomics identification Reference proteome Zinc |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | CDA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999381] ENSEMBL:ENSG00000158825 CDA [Homo sapiens] |
| secondaryIdentifier | CDD_HUMAN |
| sequenceLength | 146 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:73461] CDA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6801377] CDA [tertiary granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:6801382] CDA [secretory granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:6801411] CDA [ficolin-1-rich granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:6801593] CDA [extracellular region] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P32320 CDA (51784)
