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Details on Person UniProt:Q9BRK5 SDF4
| Class:Id | ReferenceGeneProduct:51468 |
|---|---|
| _chainChangeLog | signal peptide:1-36 added on Fri February 6 2015;chain:37-362 added on Fri February 6 2015 |
| _displayName | UniProt:Q9BRK5 SDF4 |
| _timestamp | 2024-11-03 19:35:22 |
| chain | signal peptide:1-36 chain:37-362 |
| checksum | 440C6990149AAE2C |
| comment | FUNCTION May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.FUNCTION Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.SUBUNIT Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.INTERACTION Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.ALTERNATIVE PRODUCTS Ubiquitous. Isoform 5 is expressed in pancreas.DOMAIN Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.SIMILARITY Belongs to the CREC family. |
| description | recommendedName: 45 kDa calcium-binding protein shortName: Cab45 alternativeName: Stromal cell-derived factor 4 shortName: SDF-4 |
| geneName | SDF4 CAB45 PSEC0034 |
| identifier | Q9BRK5 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Calcium Cell membrane Cell projection Cytoplasm Exocytosis Glycoprotein Golgi apparatus Membrane Metal-binding Phosphoprotein Proteomics identification Reference proteome Repeat Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | SDF4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8960169] ENSEMBL:ENSG00000078808 SDF4 [Homo sapiens] |
| secondaryIdentifier | CAB45_HUMAN B1AME5 B1AME6 B2RDF1 B4DSM1 Q53G52 Q53HQ9 Q8NBQ3 Q96AA1 Q9NZP7 Q9UN53 |
| sequenceLength | 362 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:435916] UniProt:Q9BRK5-1 SDF4 [Homo sapiens] [ReferenceIsoform:435917] UniProt:Q9BRK5-2 SDF4 [Homo sapiens] [ReferenceIsoform:435918] UniProt:Q9BRK5-3 SDF4 [Homo sapiens] [ReferenceIsoform:435919] UniProt:Q9BRK5-4 SDF4 [Homo sapiens] [ReferenceIsoform:435920] UniProt:Q9BRK5-5 SDF4 [Homo sapiens] [ReferenceIsoform:8971359] UniProt:Q9BRK5-6 SDF4 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:8960644] SDF4 [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9BRK5 SDF4 (51468)
