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Details on Person UniProt:Q9Y6N8 CDH10
| Class:Id | ReferenceGeneProduct:51228 |
|---|---|
| _chainChangeLog | signal peptide:1-22 added on Fri February 6 2015;propeptide:23-54 added on Fri February 6 2015;chain:55-788 added on Fri February 6 2015 |
| _displayName | UniProt:Q9Y6N8 CDH10 |
| _timestamp | 2024-11-03 20:18:11 |
| chain | signal peptide:1-22 propeptide:23-54 chain:55-788 |
| checksum | E92908F9C19270B2 |
| comment | FUNCTION Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.SUBCELLULAR LOCATION Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.DOMAIN Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. |
| description | recommendedName: Cadherin-10 alternativeName: T2-cadherin |
| geneName | CDH10 |
| identifier | Q9Y6N8 |
| isSequenceChanged | FALSE |
| keyword | Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Phosphoprotein Proteomics identification Reference proteome Repeat Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CDH10 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997041] ENSEMBL:ENSG00000040731 CDH10 [Homo sapiens] |
| secondaryIdentifier | CAD10_HUMAN Q9ULB3 |
| sequenceLength | 788 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:418971] CDH10 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9Y6N8 CDH10 (51228)
