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Details on Person Bmal1:Clock,Npas2 [cytosol]

Class:Id	Complex:508648
_displayName	Bmal1:Clock,Npas2 [cytosol]
_timestamp	2015-01-15 22:38:47
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:508676] May, B, 2010-02-15
hasComponent	[DefinedSet:508724] Clock,Npas2 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:508660] Arntl [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:400383] CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock [LiteratureReference:400260] Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression [LiteratureReference:508632] Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK [LiteratureReference:400240] BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer [LiteratureReference:5663152] Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex
modified	[InstanceEdit:508750] May, B, 2010-02-15 [InstanceEdit:549380] May, B, 2010-03-21 [InstanceEdit:1478317] May, B, 2011-08-10 [InstanceEdit:5252142] May, B, 2014-02-05 [InstanceEdit:5663195] May, Bruce, 2015-01-15
name	Bmal1:Clock,Npas2
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1111250] R-MMU-508648.1
(hasComponent)	[Complex:549343] Bmal1:Clock,Npas2:Cry [cytosol] [Mus musculus]
(inferredFrom)	[Complex:400360] BMAL1:CLOCK,NPAS2 [cytosol] [Homo sapiens]
(input)	[Reaction:549451] Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2 [Mus musculus]
(output)	[Reaction:508619] Bmal1 binds Clock,Npas2 forming Bmal1:Clock,Npas2 heterodimer [Mus musculus]
(updatedInstance)	[_UpdateTracker:9870634] Update Tracker - [Complex:508648] Bmal1:Clock,Npas2 [cytosol] - v38:[modifyName, updateContainedComponent] [_UpdateTracker:9888776] Update Tracker - [Complex:508648] Bmal1:Clock,Npas2 [cytosol] - v48:[modifyName, updateContainedComponent] [_UpdateTracker:9891636] Update Tracker - [Complex:508648] Bmal1:Clock,Npas2 [cytosol] - v52:[addLiteratureReference]
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No pathways have been reviewed or authored by Bmal1:Clock,Npas2 [cytosol] (508648)