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Details on Person Bmal1 binds Clock,Npas2 forming Bmal1:Clock,Npas2 heterodimer

Class:Id	Reaction:508619
_displayName	Bmal1 binds Clock,Npas2 forming Bmal1:Clock,Npas2 heterodimer
_doRelease	FALSE
_timestamp	2025-02-19 16:08:18
authored	[InstanceEdit:517836] May, B, 2010-02-20
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:508676] May, B, 2010-02-15
edited	[InstanceEdit:517836] May, B, 2010-02-20
input	[EntityWithAccessionedSequence:508660] Arntl [cytosol] [Mus musculus] [DefinedSet:508724] Clock,Npas2 [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:508642] Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators [LiteratureReference:400383] CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock [LiteratureReference:508691] Role of the CLOCK protein in the mammalian circadian mechanism [LiteratureReference:400260] Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression
modified	[InstanceEdit:508750] May, B, 2010-02-15 [InstanceEdit:517941] May, B, 2010-02-20 [InstanceEdit:549380] May, B, 2010-03-21 [InstanceEdit:766127] May, B, 2010-05-21 [InstanceEdit:847704] May, B, 2010-05-30 [InstanceEdit:879757] May, B, 2010-06-23 [InstanceEdit:927716] May, B, 2010-08-06 [InstanceEdit:5251386] May, B, 2014-02-03 [InstanceEdit:5251722] May, B, 2014-02-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9938718] May, Bruce, 2025-02-19
name	Bmal1 binds Clock,Npas2 forming Bmal1:Clock,Npas2 heterodimer
output	[Complex:508648] Bmal1:Clock,Npas2 [cytosol] [Mus musculus]
precedingEvent	[BlackBoxEvent:508681] Expression of Bmal1 (Arntl) [Mus musculus]
releaseDate	2010-09-21
reviewed	[InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1104468] R-MMU-508619.2
summation	[Summation:508649] Bmal1 (Arntl), Clock, and Npas2 are basic helix-loop-helix t...
(replacementInstances)	[_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032442] Deletion of instance: 508751
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No pathways have been reviewed or authored by Bmal1 binds Clock,Npas2 forming Bmal1:Clock,Npas2 heterodimer (508619)