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Details on Person Jupe, S, 2010-02-12

Class:IdInstanceEdit:508450
_displayNameJupe, S, 2010-02-12
_timestamp2010-02-12 11:30:46
author[Person:391309] Jupe, Steve
dateTime2010-02-12 16:30:16
(created)[Person:508436] Gao, C
[LiteratureReference:508437] Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function
[Complex:508438] IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] [Homo sapiens]
[Person:508439] Nogueira, L
[CatalystActivity:508440] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]
[Summation:508441] The proline rich tyrosine kinase 2 (PYK2) is a nonreceptor p...
[LiteratureReference:508442] Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway
[LiteratureReference:508443] Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit
[Person:508444] Benczik, M
[LiteratureReference:508445] A Pyk2-Vav1 complex is recruited to beta3-adhesion sites to initiate Rho activation
List all 16 refering instances
(modified)[Pathway:451927] Interleukin-2 family signaling [Homo sapiens]
[Summation:451944] Interleukin-2 (IL-2) is a cytokine that is produced by T cel...
[Reaction:508282] SYK is a substrate for JAK1 [Homo sapiens]
[Summation:508291] Syk binds to the serine-rich (aa 267 to 322) S region of IL2...
[Reaction:508292] SYK binds IL2RB [Homo sapiens]
[Summation:508299] Studies have shown that coexpression of Syk with catalytical...
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No pathways have been reviewed or authored by Jupe, S, 2010-02-12 (508450)