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Details on Person RAS85D:GTP complex is hydrolysed by Ras GAP

Class:Id	Reaction:508410
_displayName	RAS85D:GTP complex is hydrolysed by Ras GAP
_doRelease	FALSE
_timestamp	2017-06-27 17:37:52
authored	[InstanceEdit:508428] Williams, MG, 2010-02-11
catalystActivity	[CatalystActivity:508411] GTPase activator activity of RAS85D:GTP:Ras GAP [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:508417] Williams, MG, 2010-02-12
figure	[Figure:947925] /figures/DrosRasRafERKA09.jpg
inferredFrom	[Reaction:209372] Human RASA1 hydrolyses Ras:GTP complex [Homo sapiens]
input	[Complex:508422] RAS85D:GTP:Ras GAP [plasma membrane] [Drosophila melanogaster]
isChimeric	FALSE
literatureReference	[LiteratureReference:443312] Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein [LiteratureReference:443086] Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway
modified	[InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	RAS85D:GTP complex is hydrolysed by Ras GAP
output	[Complex:508405] RAS85D:GDP:Ras GAP [plasma membrane] [Drosophila melanogaster] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:508409] Ras GAP binds to RAS85D:GTP complex at the plasma membrane [Drosophila melanogaster] [Reaction:508415] SOS dissociates from RAS85D:GTP complex [Drosophila melanogaster] [Reaction:508432] Ras GAP dissociates from RAS85D:GDP complex [Drosophila melanogaster] [Reaction:443280] VAP binds to phosphorylated TOR receptor [Drosophila melanogaster] [Reaction:443097] VAP binds to phosphorylated FGFR [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8893905] R-DME-508410.1
summation	[Summation:508424] The GTPase-activating protein, GAP1 (in the Sevenless, EGFR,...
(hasEvent)	[Pathway:508419] Ras GTPase cycle [Drosophila melanogaster]
(precedingEvent)	[Reaction:508432] Ras GAP dissociates from RAS85D:GDP complex [Drosophila melanogaster]
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No pathways have been reviewed or authored by RAS85D:GTP complex is hydrolysed by Ras GAP (508410)