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Details on Person Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics

Class:IdLiteratureReference:508368
_displayNameCrystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
_timestamp2010-02-11 23:52:56
author[Person:508386] Kissinger, CR
[Person:508367] Rejto, PA
[Person:508380] Pelletier, LA
[Person:508378] Thomson, JA
[Person:508385] Showalter, RE
[Person:508382] Abreo, MA
[Person:508387] Agree, CS
[Person:508371] Margosiak, S
[Person:508372] Meng, JJ
[Person:508366] Aust, RM
[Person:508370] Vanderpool, D
[Person:77202] Li, B
[Person:508384] Tempczyk-Russell, A
[Person:508388] Villafranca, JE
created[InstanceEdit:508376] D'Eustachio, P, 2010-02-11
journalJ Mol Biol
modified[InstanceEdit:508390] D'Eustachio, P, 2010-02-11
pages943-52
pubMedIdentifier15342248
titleCrystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
volume342
year2004
(literatureReference)[Reaction:70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ [Homo sapiens]
[Reaction:508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ [Homo sapiens]
[Complex:508381] HSD17B10 tetramer [mitochondrial matrix] [Homo sapiens]
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