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Details on Person UniProt:H3BRN8 PIERCE2
| Class:Id | ReferenceGeneProduct:5083148 |
|---|---|
| _chainChangeLog | chain:1-121 added on Fri February 6 2015 |
| _displayName | UniProt:H3BRN8 PIERCE2 |
| _timestamp | 2024-11-03 19:38:10 |
| chain | chain:1-121 |
| checksum | 7B799AC08A1B561A |
| comment | FUNCTION Microtubule inner protein involved in the attachment of outer dynein arms (ODAs) to dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.SUBUNIT Microtubule inner protein component of sperm flagellar doublet microtubules (By similarity). Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme (By similarity).INTERACTION Expressed in airway epithelial cells.SIMILARITY Belongs to the PIERCE2 family. |
| created | [InstanceEdit:5083144] Weiser, JD |
| description | recommendedName: fullName evidence="5"Piercer of microtubule wall 2 protein |
| geneName | PIERCE2 C15orf65 |
| identifier | H3BRN8 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell projection Cilium Cytoplasm Cytoskeleton Flagellum Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PIERCE2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999402] ENSEMBL:ENSG00000261652 PIERCE2 [Homo sapiens] |
| secondaryIdentifier | PIRC2_HUMAN |
| sequenceLength | 121 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:9966884] PIERCE2 [cilium] [Homo sapiens] [EntityWithAccessionedSequence:9969200] PIERCE2 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:H3BRN8 PIERCE2 (5083148)
