Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person UniProt:H3BTG2-2 TEX46

Class:IdReferenceIsoform:5083147
_chainChangeLogsignal peptide:1-38 added on Fri February 6 2015;chain:39-121 added on Fri February 6 2015;signal peptide:1-38 for 5083147 removed on Fri Feb 21 2025;chain:39-121 for 5083147 removed on Fri Feb 21 2025;signal peptide:1-17 for 5083147 added on Fri Feb 21 2025;chain:18-121 for 5083147 added on Fri Feb 21 2025
_displayNameUniProt:H3BTG2-2 TEX46
_timestamp2025-08-15 22:17:39
chainsignal peptide:1-17
chain:18-121
checksum8693956F10C5DBD6
commentFUNCTION Essential for male fertility, sperm head formation and sperm penetration through the egg zona pellucida.SUBCELLULAR LOCATION Testis-specific.
created[InstanceEdit:5083144] Weiser, JD
descriptionrecommendedName: Testis-expressed protein 46
geneNameTEX46
C1orf234
identifierH3BTG2
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
Fertilization
Membrane
Proteomics identification
Reference proteome
Signal
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
[InstanceEdit:9939033] Weiser, Joel, 2025-02-21
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
nameTEX46
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8995312] ENSEMBL:ENSG00000227868 TEX46 [Homo sapiens]
secondaryIdentifierTEX46_HUMAN
H3BR39
sequenceLength121
species[Species:48887] Homo sapiens
variantIdentifierH3BTG2-2
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No pathways have been reviewed or authored by UniProt:H3BTG2-2 TEX46 (5083147)