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Details on Person SYK binds IL2RB

Class:IdReaction:508292
_displayNameSYK binds IL2RB
_doReleaseTRUE
_timestamp2017-12-08 18:23:24
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:508272] Jupe, S, 2010-02-11
edited[InstanceEdit:924611] Jupe, S, 2010-08-06
input[Complex:451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:58268] SYK [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:508284] Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway
modified[InstanceEdit:508450] Jupe, S, 2010-02-12
[InstanceEdit:918253] Jupe, S, 2010-08-02
[InstanceEdit:926765] Jupe, S, 2010-08-06
[InstanceEdit:941875] Jupe, S, 2010-09-06
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1168657] Jupe, S, 2011-01-05
[InstanceEdit:1213522] Jupe, S, 2011-02-11
[InstanceEdit:1233244] Jupe, S, 2011-03-17
[InstanceEdit:8942546] Jupe, Steve, 2016-10-18
[InstanceEdit:9020559] Duenas, Corina, 2017-09-07
[InstanceEdit:9032271] Orlic-Milacic, Marija, 2017-12-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSYK binds IL2RB
output[Complex:508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2011-03-15
reviewed[InstanceEdit:1213492] Villarino, A, 2011-02-11
[InstanceEdit:1233246] Dooms, H, 2011-03-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1225075] R-HSA-508292.5
summation[Summation:508291] Syk binds to the serine-rich (aa 267 to 322) S region of IL2...
(hasEvent)[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent)[Reaction:508282] SYK is a substrate for JAK1 [Homo sapiens]
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