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Details on Person p85-containing Class 1A PI3Ks [cytosol]

Class:IdDefinedSet:508248
_displayNamep85-containing Class 1A PI3Ks [cytosol]
_timestamp2010-12-02 14:48:28
compartment[Compartment:70101] cytosol
created[InstanceEdit:508240] Jupe, S, 2010-02-11
hasMember
modified[InstanceEdit:508250] Jupe, S, 2010-02-11
[InstanceEdit:912521] Jupe, S, 2010-07-09
[InstanceEdit:912661] Jupe, S, 2010-07-12
namep85-containing Class 1A PI3Ks
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1107544] R-HSA-508248.1
summation[Summation:508237] This set represents Class 1A PI3Ks including all three genes...
(hasComponent)[Complex:508238] IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
[Complex:912532] IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
[Complex:912623] FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] [Homo sapiens]
[Complex:912647] FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] [Homo sapiens]
[Complex:914177] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
[Complex:926773] High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
[Complex:926774] High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
[Complex:8855523] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] [Homo sapiens]
(input)[Reaction:508247] Gab2 binds the p85 subunit of Class 1A PI3 kinases [Homo sapiens]
[Reaction:879917] CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated [Homo sapiens]
[Reaction:914182] 14-3-3 zeta binding allows recruitment of PI3K [Homo sapiens]
[BlackBoxEvent:8854905] p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K [Homo sapiens]
(updatedInstance)[_UpdateTracker:9875360] Update Tracker - [DefinedSet:508248] p85-containing Class 1A PI3Ks [cytosol] - v44:[updateContainedMemberOrCandidate]
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No pathways have been reviewed or authored by p85-containing Class 1A PI3Ks [cytosol] (508248)
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