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Details on Person GAB2 [cytosol]

Class:Id	EntityWithAccessionedSequence:508239
_displayName	GAB2 [cytosol]
_timestamp	2010-12-02 15:04:48
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:508240] Jupe, S, 2010-02-11
endCoordinate	676
modified	[InstanceEdit:508250] Jupe, S, 2010-02-11 [InstanceEdit:3448660] Wu, G, 2013-05-16
name	GAB2 GRB2-associated-binding protein 2 GAB2_HUMAN
referenceEntity	[ReferenceGeneProduct:147728] UniProt:Q9UQC2 GAB2 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1112021] R-HSA-508239.1
startCoordinate	1
(hasComponent)	[Complex:912522] GRB2:GAB2 [cytosol] [Homo sapiens] [Complex:1433545] GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] [Homo sapiens] [Complex:2685701] p-10Y-NTAL:p-SHC1:GRB2:SOS:GAB2 [plasma membrane] [Homo sapiens] [Complex:8983327] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 [plasma membrane] [Homo sapiens] [Complex:9606619] Active FLT3:GRB2:GAB2 [plasma membrane] [Homo sapiens] [Complex:9697974] p-6Y FLT3 mutant dimers:GRB2:GAB2 [plasma membrane] [Homo sapiens] [Complex:9703352] p-Y FLT3 fusions:GRB2:GAB2 [cytosol] [Homo sapiens]
(hasMember)	[DefinedSet:8855092] GAB1,GAB2 [cytosol] [Homo sapiens]
(input)	[Reaction:205234] Indirect recruitment of GAB2 to p-KIT [Homo sapiens] [Reaction:2730848] Recruitment of GAB2 to PM and FCERI by binding to GRB2 [Homo sapiens] [BlackBoxEvent:8983425] IL15:IL15RA:IL2RB:JAK1:IL2RG:p-JAK3:p-Y-SHC1:GRB2 binds GAB2 [Homo sapiens] [Reaction:9606624] Active FLT3:GRB2 binds GAB2 [Homo sapiens] [BlackBoxEvent:9674808] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) [Homo sapiens] [Reaction:9698000] FLT3 mutants:GRB2 bind GAB2 [Homo sapiens] [Reaction:9703440] FLT3 fusions:GRB2 bind GAB2 [Homo sapiens]
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No pathways have been reviewed or authored by GAB2 [cytosol] (508239)