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Details on Person p-S326-HSF1 trimer [nucleoplasm]

Class:Id	Complex:5082354
_displayName	p-S326-HSF1 trimer [nucleoplasm]
_timestamp	2014-11-20 03:40:09
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5082352] Shamovsky, V, 2013-11-05
hasComponent	[EntityWithAccessionedSequence:5082355] p-S326-hC36,103-HSF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5082355] p-S326-hC36,103-HSF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5082355] p-S326-hC36,103-HSF1 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4793831] Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription
name	p-S326-HSF1 trimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5647010] R-HSA-5082354.1
(hasComponent)	[Complex:9857078] ATF5:HSF1 trimer:HSPD1 gene:HSPE1 gene [nucleoplasm] [Homo sapiens] [Complex:9857094] ATF5:HSF1 trimer:HSPA9 gene [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9857071] ATF5 and HSF1 trimer bind the bidirectional promoter of the HSPD1 gene and HSPE1 gene [Homo sapiens] [Reaction:9857083] ATF5 and HSF1 trimer bind the HSPA9 gene [Homo sapiens]
(output)	[Reaction:5082405] Phosphorylation of HSF1 at Ser326 induces transactivation [Homo sapiens] [BlackBoxEvent:9857091] HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization [Homo sapiens]
(regulator)	[PositiveGeneExpressionRegulation:5082359] Positive gene expression regulation by 'p-S326-HSF1 trimer [nucleoplasm]'
(requiredInputComponent)	[BlackBoxEvent:9856627] ATF5 and HSF1 trimer activate expression of HSPA9 (mtHSP70) [Homo sapiens]
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No pathways have been reviewed or authored by p-S326-HSF1 trimer [nucleoplasm] (5082354)