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Details on Person Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin
| Class:Id | LiteratureReference:508185 |
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| _displayName | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin |
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| _timestamp | 2010-02-10 23:39:43 |
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| author | [Person:508186] Goto, M
[Person:508180] Miyahara, I
[Person:508184] Hirotsu, K
[Person:70708] Conway, ME
[Person:70706] Yennawar, NH
[Person:508191] Islam, MM
[Person:70709] Hutson, Susan M |
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| created | [InstanceEdit:508183] D'Eustachio, P, 2010-02-10 |
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| journal | J Biol Chem |
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| modified | [InstanceEdit:508193] D'Eustachio, P, 2010-02-10 |
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| pages | 37246-56 |
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| pubMedIdentifier | 16141215 |
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| title | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin |
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| volume | 280 |
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| year | 2005 |
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| (literatureReference) | [Reaction:70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Homo sapiens]
[Reaction:508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Homo sapiens]
[Complex:70699] BCAT1 dimer [cytosol] [Homo sapiens]
[CatalystActivityReference:9643740] branched-chain-amino-acid transaminase activity of BCAT1 dimer [cytosol] Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin |
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